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Article

Rck2 kinase is a substrate for the osmotic stress-activated mitogen-activated protein kinase Hog1.

Molecular and cellular biology - 1 Jun 2000

Bilsland-Marchesan E, Ariño J, Saito H, Sunnerhagen P, Posas F

Abstract excerpt

Exposure of yeast cells to increases in extracellular osmolarity activates the Hog1 mitogen-activated protein kinase (MAPK). Activation of Hog1 MAPK results in induction of a set of osmoadaptive responses, which allow cells to survive in high-osmolarity environments. Little is known about how the MAPK activation results in induction of these responses, mainly because no direct substrates for Hog1 have been...

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Identifiers

PMID: 10805732
DOI: 10.1128/MCB.20.11.3887-3895.2000
PMCID: PMC85729

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Rck2 kinase is a substrate for the osmotic stress-activated mitogen-activated protein kinase Hog1.PMID 10805732Read ↗

Identifying protein kinase-specific effectors of the osmostress response in yeast.Semantic proximity Read ↗

Osmostress induces autophosphorylation of Hog1 via a C-terminal regulatory region that is conserved in p38α.Semantic proximity Read ↗

Evidence of a new role for the high-osmolarity glycerol mitogen-activated protein kinase pathway in yeast: regulating adaptation to citric acid stress.Semantic proximity Read ↗

MAPK Hog1 closes the S. cerevisiae glycerol channel Fps1 by phosphorylating and displacing its positive regulators.Semantic proximity Read ↗

Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway.Semantic proximity Read ↗

Unique and redundant roles for HOG MAPK pathway components as revealed by whole-genome expression analysis.Semantic proximity Read ↗

Human mitogen-activated protein kinase CSBP1, but not CSBP2, complements a hog1 deletion in yeast.Semantic proximity Read ↗

The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes.Semantic proximity Read ↗

Activation of the Saccharomyces cerevisiae filamentation/invasion pathway by osmotic stress in high-osmolarity glycogen pathway mutants.Semantic proximity Read ↗

Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases.Semantic proximity Read ↗

Crosstalk between Saccharomycescerevisiae SAPKs Hog1 and Mpk1 is mediated by glycerol accumulation.Semantic proximity Read ↗

MAPKKK-independent regulation of the Hog1 stress-activated protein kinase in Candida albicans.Semantic proximity Read ↗

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