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Article

Crosstalk between Saccharomycescerevisiae SAPKs Hog1 and Mpk1 is mediated by glycerol accumulation.

Fungal biology - 1 May 2020

Laz Ekaterina V, Lee Jongmin, Levin David E

Abstract excerpt

Two stress-activated MAP kinase (SAPK) pathways in Saccharomyces cerevisiae respond to osmotic imbalances. The High Osmolarity Glycerol (HOG) pathway is activated in response to hyper-osmotic stress, whereas the Cell Wall Integrity (CWI) pathway is activated in response to hypo-osmotic stress. However, there is also evidence of complex interplay and crosstalk between the two pathways. For example, treatment with...

Topics

Enzyme Activation
Glycerol
Mitogen-Activated Protein Kinases
Mutation
Osmotic Pressure
Phosphorylation
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32389298
DOI: 10.1016/j.funbio.2019.10.002
PMCID: PMC7217976

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-32389298-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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