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Article

Human mitogen-activated protein kinase CSBP1, but not CSBP2, complements a hog1 deletion in yeast.

The Journal of biological chemistry - 8 Dec 1995

Kumar S, McLaughlin M M, McDonnell P C, Lee J C, Livi G P, Young P R

Abstract excerpt

CSBP1 and CSBP2 are human homologues of the Saccharomyces cerevisiae Hog1 mitogen-activated protein kinase which is required for growth in high osmolarity media. Expression of CSBP1, but not CSBP2, complemented a hog1 delta phenotype. A CSBP2 mutant (A34V) that complements hog1 delta was isolated and found to have approximately 3-fold lower kinase activity than the wild-type CSBP2. Further analysis revealed that...

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PMID: 7493921
DOI: 10.1074/jbc.270.49.29043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Human mitogen-activated protein kinase CSBP1, but not CSBP2, complements a hog1 deletion in yeast.PMID 7493921Read ↗

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