Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Survival in operable non-small-cell lung cancer: role of p53 mutations, tobacco smoking and asbestos exposure.

International journal of cancer - 15 May 2000

Sioris T, Husgafvel-Pursiainen K, Karjalainen A, Anttila S, Kannio A, Salo J A, Perhoniemi V, Heikkilä L, Vainio H

Abstract excerpt

Validated markers are needed to identify operable lung cancer patients with poor prognosis. About one-half of non-small-cell lung cancers (NSCLCs) carry a mutation in the p53 tumor-suppressor gene. We examined 101 NSCLC patients for surgical stage, completeness of resection, tobacco smoking, asbestos exposure, age, gender and p53 gene mutations as prognostic factors after a follow-up period of 4 years. Cox's...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Asbestos

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Non-Small-Cell Lung

Share to Genes, p53

Share to Lung Neoplasms

Share to Prognosis

Share to Smoking

Share to Survival Rate

Source

Identifiers

PMID: 10797276
DOI: 10.1002/(sici)1097-0215(20000515)86:4<590::aid-ijc23>3.0.co;2-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Survival in operable non-small-cell lung cancer: role of p53 mutations, tobacco smoking and asbestos exposure.PMID 10797276Read ↗

p53 mutations and survival in stage I non-small-cell lung cancer: results of a prospective study.Semantic proximity Read ↗

Mutations of the p53 gene as a predictor of poor prognosis in patients with non-small-cell lung cancer.Semantic proximity Read ↗

Prognostic significance of p53 mutations in non-small cell lung cancer: a meta-analysis of 829 cases from eight published studies.Semantic proximity Read ↗

Mutations of p53 and K-ras genes as prognostic factors for non-small cell lung cancer.Semantic proximity Read ↗

Prognostic and predictive importance of p53 and RAS for adjuvant chemotherapy in non small-cell lung cancer.Semantic proximity Read ↗

Prognostic significance of p53 alterations in patients with non-small cell lung cancer: a meta-analysis.Semantic proximity Read ↗

Association between p53 mutation and clinicopathological features of non-small cell lung cancer.Semantic proximity Read ↗

Deep sequencing of the TP53 gene reveals a potential risk allele for non-small cell lung cancer and supports the negative prognostic value of TP53 variants.Semantic proximity Read ↗

Significance of TP53 mutations as predictive markers of adjuvant cisplatin-based chemotherapy in completely resected non-small-cell lung cancer.Semantic proximity Read ↗

An association between DNA repair gene polymorphisms and survival in patients with resected non-small cell lung cancer.Semantic proximity Read ↗

Prognostic and Predictive Effect of TP53 Mutations in Patients with Non-Small Cell Lung Cancer from Adjuvant Cisplatin-Based Therapy Randomized Trials: A LACE-Bio Pooled Analysis.Semantic proximity Read ↗

TP53 and MDM2 genetic alterations in non-small cell lung cancer: Evaluating their prognostic and predictive value.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.