Article
Prognostic significance of p53 mutations in non-small cell lung cancer: a meta-analysis of 829 cases from eight published studies.
Cancer letters - 29 May 2000
Huncharek M, Kupelnick B, Geschwind J F, Caubet J F
Abstract excerpt
Mutation of the p53 tumor suppressor gene is considered a possible marker of poor survival among patients with non-small cell lung cancer (NSCLC). This report presents the results of a meta-analysis of the available data addressing this issue. Using previously described methods, a protocol was developed for a meta-analysis examining the prognostic significance of p53 mutations in NSCLC. Two-year survival data...
Topics
- Biomarkers, Tumor
- Carcinoma, Non-Small-Cell Lung
- Clinical Trials as Topic
- Humans
- Lung Neoplasms
- Mutation
- Polymorphism, Single-Stranded Conformational
- Prognosis
- Tumor Suppressor Protein p53
