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Article

p53 mutations and survival in stage I non-small-cell lung cancer: results of a prospective study.

Journal of the National Cancer Institute - 2 Jul 2003

Ahrendt Steven A, Hu Yingchuan, Buta Martin, McDermott Michael P, Benoit Nicole, Yang Stephen C, Wu Li, Sidransky David

Abstract excerpt

BACKGROUND: The p53 gene is frequently mutated in non-small-cell lung cancer (NSCLC); however, the effect of p53 gene mutations on patient prognosis remains unclear. Therefore, we initiated a prospective study to determine the association of p53 gene mutations with survival in patients with stage I NSCLC. METHODS: Tumor samples were collected prospectively from 188 patients with operable NSCLC (stages I, II, and...

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Identifiers

PMID: 12837832
DOI: 10.1093/jnci/95.13.961

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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