Article
An association between DNA repair gene polymorphisms and survival in patients with resected non-small cell lung cancer.
Molecular biology reports - 1 Nov 2011
Butkiewicz Dorota, Rusin Marek, Sikora Bożena, Lach Antonina, Chorąży Mieczysław
Abstract excerpt
DNA repair genetic polymorphisms have been studied extensively in relation to lung cancer susceptibility, but much less is known about their role in clinical outcome modulation. In this report, we examined effect of the XPA -4G>A, XPD Asp312Asn, Leu751Gln, hHR23B Ala249Val, XPG Asp1104His, XRCC1 Arg399Gln, XRCC2 -4234G>C and XRCC3 Thr241Met polymorphisms on overall survival in 162 patients with resected non-small...
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