Article
Identification of two polymorphisms in the early growth response protein-1 gene: possible association with lipid variables.
Journal of molecular medicine (Berlin, Germany) - 1 Jan 2000
Brand E, Herrmann S M, Nicaud V, Evans A, Ruidavets J B, Arveiler D, Luc G, Cambien F, Soubrier F
Abstract excerpt
Early growth response factor (EGR)-1 may play an important role in the development of atherosclerosis by inducing the expression of several relevant genes which contribute to the complex modulation of vascular structure and function, leading to vascular occlusive lesions. To investigate the possible role of molecular variants in the human EGR-1 gene for the predisposition to atherosclerosis or coronary heart...
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