Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High expressor paraoxonase PON1 gene promoter polymorphisms are associated with reduced risk of vascular disease in younger coronary patients.

Atherosclerosis - 1 Apr 2002

Leviev Ilia, Poirier Odette, Nicaud Viviane, Evans Alun, Kee Frank, Arveiler Dominique, Morrisson Caroline, Cambien François, James Richard W

Abstract excerpt

Human paraoxonase-1 is hypothesised to protect serum lipoproteins from oxidative stress. Decreased serum activity of paraoxonase-1 in animal models is associated with an increased risk of vascular disease and has been linked to the anti-oxidant capacity of the enzyme. Promoter polymorphisms of the human paraoxonase-1 gene strongly influence serum concentrations of the enzyme. The present study examined the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryldialkylphosphatase
Share to Confidence Intervals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Disease

Share to Esterases

Share to Linear Models

Share to Reference Values

Share to Risk Assessment

Share to Vascular Diseases

Source

Identifiers

PMID: 11888532
DOI: 10.1016/s0021-9150(01)00668-2

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High expressor paraoxonase PON1 gene promoter polymorphisms are associated with reduced risk of vascular disease in younger coronary patients.PMID 11888532Read ↗

Promoter polymorphism T(-107)C of the paraoxonase PON1 gene is a risk factor for coronary heart disease in type 2 diabetic patients.Semantic proximity Read ↗

Paraoxonase promoter polymorphism T(-107)C and relative paraoxonase deficiency as determinants of risk of coronary artery disease.Semantic proximity Read ↗

Paraoxonase 1 activity, concentration and genotype in cardiovascular diseaseSemantic proximity Read ↗

The combined effect of paraoxonase promoter and coding region polymorphisms on the risk of arterial ischemic stroke among young adults.Semantic proximity Read ↗

Variation at the paraoxonase gene locus contributes to carotid arterial wall thickness in subjects with familial hypercholesterolemia.Semantic proximity Read ↗

Paraoxonase (PON1) and the risk for coronary heart disease and myocardial infarction in a general population of Dutch women.Semantic proximity Read ↗

Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia.Semantic proximity Read ↗

The correlation of paraoxonase (PON1) activity with lipid and lipoprotein levels differs with vascular disease status.Semantic proximity Read ↗

Modulation of the antioxidant enzyme paraoxonase-1 for protection against cardiovascular diseases.Semantic proximity Read ↗

Paraoxonase2 C311S polymorphism and low levels of HDL contribute to a higher mortality risk after acute myocardial infarction in elderly patients.Semantic proximity Read ↗

Polymorphisms in the human paraoxonase (PON1) promoterSemantic proximity Read ↗

Association between serum paraoxonase (PON1) gene promoter T(-107)C polymorphism, PON1 activity and HDL levels in healthy Sicilian octogenarians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.