Article
Association between the Advanced Glycosylation End Product-Specific Receptor Gene and Cardiovascular Death in Older Men.
PloS one - 1 Jan 2015
Biros Erik, Moran Corey S, Norman Paul E, Hankey Graeme J, Yeap Bu B, Almeida Osvaldo P, Flicker Leon, White Richard, Jones Rhondda, Golledge Jonathan
Abstract excerpt
Advanced glycosylation end product-specific receptor (AGER) signaling has been implicated in atherosclerosis. The aim of this study was to evaluate whether a common genetic variation in the AGER gene is associated with cardiovascular (CV) death. We included 1304 older men who were genotyped for rs1035798:C>T, which is a single nucleotide polymorphism (SNP) mapped to the third intron of AGER. Cox proportional...
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