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Article

Early growth response-1, a dynamic conduit in cardiovascular disease

15 Nov 2024

Abstract excerpt

The transcription factor, early growth response-1 (Egr-1) is the product of a prototypic immediate-early gene that plays an integral role in the pathogenesis of multiple cardiovascular diseases. Egr-1 has been linked with atherogenesis, myocardial ischemia-reperfusion injury, cardiac fibrosis and heart failure. Egr-1 expression is triggered by a host of factors including cytokines, hormones, growth factors,...

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PMID: 39619154
DOI: 10.3389/fcvm.2024.1487668

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