Article
Cognitive function and apolipoprotein E in very old adults: findings from the Nun Study.
The journals of gerontology. Series B, Psychological sciences and social sciences - 1 Mar 2000
Riley K P, Snowdon D A, Saunders A M, Roses A D, Mortimer J A, Nanayakkara N
Abstract excerpt
OBJECTIVES: The epsilon4 allele of apolipoprotein E (APOE) has been associated with Alzheimer' s disease and with milder forms of cognitive impairment. We investigated the possibility that the absence of the epsilon4 allele may predict the maintenance of high cognitive function among very old individuals. METHODS: Our data are from the Nun Study, a longitudinal study of aging and Alzheimer's disease in 678...
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