Article
Apolipoprotein e genotypes: relationship to cognitive functioning, cognitive decline, and survival in nonagenarians.
Journal of the American Geriatrics Society - 1 Apr 2006
Bathum Lise, Christiansen Lene, Jeune Bernard, Vaupel James, McGue Matt, Christensen Kaare
Abstract excerpt
OBJECTIVES: To evaluate the extent to which relationships between apolipoprotein E, cognitive functioning, and survival in people aged 60 to 80 persist into advanced old age. DESIGN: Examine the effect of apolipoprotein E genotypes on baseline cognitive functioning, cognitive decline over 5 years, and survival in a cohort of 1,551 nonagenarians. SETTING: The Danish 1905 birth cohort. PARTICIPANTS: One thousand...
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