Article
CTLA4 exon 1 dimorphism in bullous and cicatricial pemphigoid.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Apr 2000
Drouet M, Aupetit C, Delpuget-Bertin N, Bedane C, Bonnetblanc J M, Cogné M
Abstract excerpt
The human cytotoxic T-lymphocyte antigen 4 (CTLA4) gene encodes proteins regulating the immune response. The polymorphism of this gene is associated with some autoimmune diseases. In this study, we analysed the distribution of the dimorphisms of exon 1 (+ 49 A/G) in bullous pemphigoid (BP) and cicatricial pemphigoid (CP), two types of autoimmune bullous skin diseases that occur in elderly people. The frequency of...
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