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Article

CTLA-4 exon 1 polymorphism in patients with autoimmune blood disorders.

American journal of hematology - 1 Feb 2003

Pavkovic Marica, Georgievski Borce, Cevreska Lidija, Spiroski Mirko, Efremov Dimitar G

Abstract excerpt

CTLA-4 is a CD28 homologue that plays an important role in negative regulation of T-cell responses. Its transient expression on the surface of activated T cells antagonizes the activating signals and terminates the T-cell response. An A to G polymorphism at position 49 of the CTLA-4 first exon has recently been associated with several autoimmune disorders. In the present study we have examined the prevalence of...

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Source

Identifiers

PMID: 12555221
DOI: 10.1002/ajh.10278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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