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Article

Exon-1 polymorphism of ctla-4 gene is not associated with systemic sclerosis in Iranian patients.

Rheumatology international - 1 Jun 2006

Rajaee A, Ebrahimi A, Ghiam A Fotouhi, Kalantari T, Ghaderi A

Abstract excerpt

Although, the cytotoxic T lymphocyte antigen-4 gene polymorphism at position 49 of exon-1 has been strongly elucidated in different autoimmune diseases, but its role in predisposition to systemic sclerosis (SSc) is yet controversial. This study intends to analyze the genetic correlation of the ctla-4 gene locus with diffuse systemic sclerosis (dSSc), as well as to understand the influence of these genotypes in...

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PMID: 16189655
DOI: 10.1007/s00296-005-0047-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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