Article
CLASP regulates mitochondrial distribution in Schizosaccharomyces pombe.
The Journal of cell biology - 14 Jul 2008
Chiron Stéphane, Bobkova Alyona, Zhou Haowen, Yaffe Michael P
Abstract excerpt
Movement of mitochondria in Schizosaccharomyces pombe depends on their association with the dynamic, or plus ends, of microtubules, yet the molecular basis for this interaction is poorly understood. We identified mmd4 in a screen of temperature-sensitive S. pombe strains for aberrant mitochondrial morphology and distribution. Cells with the mmd4 mutation display mitochondrial aggregation near the cell ends at...
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