Article
Functional dissection and hierarchy of tubulin-folding cofactor homologues in fission yeast.
Molecular biology of the cell - 1 Sept 1999
Radcliffe P A, Hirata D, Vardy L, Toda T
Abstract excerpt
We describe the isolation of fission yeast homologues of tubulin-folding cofactors B (Alp11) and E (Alp21), which are essential for cell viability and the maintenance of microtubules. Alp11(B) contains the glycine-rich motif (the CLIP-170 domain) involved in microtubular functions, whereas, unlike mammalian cofactor E, Alp21(E) does not. Both mammalian and yeast cofactor E, however, do contain leucine-rich...
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