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Article

Absence of H- and K-ras oncogene mutations in sporadic medullary thyroid carcinoma.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Jan 2000

Bockhorn M, Frilling A, Kalinin V, Schröder S, Broelsch C E

Abstract excerpt

Medullary thyroid carcinoma (MTC) occurs sporadically (sMTC) or as part of the inherited cancer syndrome, multiple endocrine neoplasia type 2 (MEN 2). While the occurence of the MEN 2 syndrome is associated with mutations in the RET protooncogene, the reason for carcinogenesis in sMTC still remains unclear. Ras is a frequently mutated oncogene in a broad spectrum of human tumors and has been found in about 50% of...

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Identifiers

PMID: 10768832
DOI: 10.1055/s-0032-1329215

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Absence of H- and K-ras oncogene mutations in sporadic medullary thyroid carcinoma.PMID 10768832Read ↗

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