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Article

No correlation between RET immunostaining and the codon 918 mutation in sporadic medullary thyroid carcinoma.

Langenbeck's archives of surgery - 1 Feb 1999

Bockhorn M, Frilling A, Kalinin V, Schröder S, Broelsch C E

Abstract excerpt

INTRODUCTION: Medullary thyroid carcinoma (MTC) occurs sporadically or as part of the inherited cancer syndrome, multiple endocrine neoplasia (MEN) type 2. The MEN2 gene has been identified as the RET proto-oncogene. Mutations in the RET proto-oncogene are associated with the pathogenesis of MTC. Approximately 23-40% of sporadic MTCs (sMTCs) have a somatic RET codon 918 mutation within the catalytic core of the...

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Identifiers

PMID: 10367632
DOI: 10.1007/s004230050175

Genes

RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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