Article
Etheno-adduct-forming chemicals: from mutagenicity testing to tumor mutation spectra.
Mutation research - 1 Apr 2000
Barbin A
Abstract excerpt
During the past 25 years, ethenobases have emerged as a new class of DNA lesions with promutagenic potential. Ethenobases were first investigated as DNA reaction products of vinyl chloride, an occupational carcinogen causing angiosarcoma of the liver (ASL). They were subsequently shown to be formed by several carcinogenic agents, including urethane (ethyl carbamate), and more recently, to occur in various tissues...
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