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Article

The stability region of the large virulence plasmid of Shigella flexneri encodes an efficient postsegregational killing system.

Journal of bacteriology - 1 May 2000

Sayeed S, Reaves L, Radnedge L, Austin S

Abstract excerpt

The large virulence plasmid pMYSH6000 of Shigella flexneri contains a determinant that is highly effective in stabilizing otherwise unstable plasmids in Escherichia coli. Expression of two small contiguous genes, mvpA and mvpT (formerly termed STBORF1 and STBORF2), was shown to be sufficient for stability. Mutations in mvpT abolished plasmid stability, and plasmids expressing only mvpT killed the cells unless...

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Identifiers

PMID: 10762240
DOI: 10.1128/JB.182.9.2416-2421.2000
PMCID: PMC111302

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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