Article

Two new plasmid post-segregational killing mechanisms for the implementation of synthetic gene networks in <i>E. coli</i>

2018-06-19

Abstract excerpt

Plasmids are the workhorse of both industrial biotechnology and synthetic biology, but ensuring they remain in bacterial cells is a challenge. Antibiotic selection, commonly used in the laboratory, cannot be used to stabilise plasmids in most real-world applications, and inserting dynamical gene networks into the genome is difficult. Plasmids have evolved several mechanisms for stability, one of which, post-segreg...

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Literature Corpus work: 9c0bf0d4-119c-53c2-af9e-5bc492c0cc8a
DOI: 10.1101/350744

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