Article
Identification and characterization of a novel allele of Escherichia coli dnaB helicase that compromises the stability of plasmid P1.
Journal of bacteriology - 1 Feb 2005
Slavcev Roderick A, Funnell Barbara E
Abstract excerpt
Bacteriophage P1 lysogenizes Escherichia coli cells as a plasmid with approximately the same copy number as the copy number of the host chromosome. Faithful inheritance of the plasmids relies upon proper DNA replication, as well as a partition system that actively segregates plasmids to new daughter cells. We genetically screened for E. coli chromosomal mutations that influenced P1 stability and identified a...
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