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Article

TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development.

Molecular and cellular biology - 1 May 2000

Takatsu Y, Nakamura M, Stapleton M, Danos M C, Matsumoto K, O'Connor M B, Shibuya H, Ueno N

Abstract excerpt

Transforming growth factor beta (TGF-beta)-activated kinase 1 (TAK1) is a member of the MAPKKK superfamily and has been characterized as a component of the TGF-beta/bone morphogenetic protein signaling pathway. TAK1 function has been extensively studied in cultured cells, but its in vivo function is not fully understood. In this study, we isolated a Drosophila homolog of TAK1 (dTAK1) which contains an extensively...

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Identifiers

PMID: 10757786
DOI: 10.1128/MCB.20.9.3015-3026.2000
PMCID: PMC85571

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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