Article
The role of the Drosophila TAK homologue dTAK during development.
Mechanisms of development - 1 Apr 2001
Mihaly J, Kockel L, Gaengel K, Weber U, Bohmann D, Mlodzik M
Abstract excerpt
The TAK kinases belong to the MAPKKK group and have been implicated in a variety of signaling events. Originally described as a TGF-beta activated kinase (TAK) it has, however, subsequently been demonstrated to signal through p38, Jun N-terminal kinase (JNK) and Nemo types of MAP kinases, and the NFkappaB inducing kinase. Despite these multiple proposed functions, the in vivo role of TAK family kinases remains...
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