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Article

Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper.

Genes & development - 1 Feb 2002

Stronach Beth, Perrimon Norbert

Abstract excerpt

The Jun kinase (JNK) pathway has been characterized for its role in stimulating AP-1 activity and for modulating the balance between cell growth and death during development, inflammation, and cancer. Six families of mammalian kinases acting at the level of JNKKK have emerged as upstream regulators of JNK activity (MLK, LZK, TAK, ASK, MEKK, and TPL); however, the specificity underlying which kinase is utilized...

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Identifiers

PMID: 11825878
DOI: 10.1101/gad.953002
PMCID: PMC155330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper.PMID 11825878Read ↗

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