Plakoglobin Regulates the Expression of the Anti-apoptotic Protein BCL-2

doi:10.1074/jbc.275.15.10905

Article

Plakoglobin Regulates the Expression of the Anti-apoptotic Protein BCL-2

1 Apr 2000

Abstract excerpt

Plakoglobin is a cytoplasmic protein and a homologue of beta-catenin and Armadillo of Drosophila with similar adhesive and signaling functions. These proteins interact with cadherins to mediate cell-cell adhesion and associate with transcription factors to induce changes in the expression of genes involved in cell fate determination and proliferation. Unlike the relatively well characterized role of beta-catenin...

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.