Article
Regulation of beta-catenin levels and localization by overexpression of plakoglobin and inhibition of the ubiquitin-proteasome system.
The Journal of cell biology - 1 Dec 1997
Salomon D, Sacco P A, Roy S G, Simcha I, Johnson K R, Wheelock M J, Ben-Ze'ev A
Abstract excerpt
beta-Catenin and plakoglobin (gamma-catenin) are closely related molecules of the armadillo family of proteins. They are localized at the submembrane plaques of cell-cell adherens junctions where they form independent complexes with classical cadherins and alpha-catenin to establish the link with...
Topics
- 3T3 Cells
- Animals
- Biological Transport
- Cell Compartmentation
- Cell Nucleus
- Cells, Cultured
- Cysteine Endopeptidases
- Cysteine Proteinase Inhibitors
- Cytoskeletal Proteins
- Desmoplakins
- Gene Expression
- Mice
- Multienzyme Complexes
- Mutation