Induction of mutual stabilization and retardation of tumor growth by coexpression of plakoglobin and E-cadherin in mouse skin spindle carcinoma cells.

doi:10.1002/(sici)1098-2744(199804)21:4<273::aid-mc6>3.0.co;2-l

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Induction of mutual stabilization and retardation of tumor growth by coexpression of plakoglobin and E-cadherin in mouse skin spindle carcinoma cells.

Molecular carcinogenesis - 1 Apr 1998

Lozano E, Cano A

Abstract excerpt

The influence of plakoglobin on the phenotype and tumorigenicity of murine spindle carcinoma cells was analyzed by stable transfection of plakoglobin cDNA in the presence or absence of E-cadherin expression. In either situation, overexpression of plakoglobin was unable to modify the fibroblastic...

Topics

Animals
Cadherins
Calcium
Carcinoma
Cell Adhesion
Cell Differentiation
Cell Line, Transformed
Cytoskeletal Proteins
DNA, Complementary
Desmoplakins
Detergents
Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Fibroblasts

Gene Expression Regulation, Neoplastic

Half-Life

Humans

Keratinocytes

Macromolecular Substances

Source

Open in PubMed

Identifiers

PMID: 9585257
DOI: 10.1002/(sici)1098-2744(199804)21:4<273::aid-mc6>3.0.co;2-l

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9585257-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction of mutual stabilization and retardation of tumor growth by coexpression of plakoglobin and E-cadherin in mouse skin spindle carcinoma cells.PMID 9585257Read ↗

Expression of E- or P-cadherin is not sufficient to modify the morphology and the tumorigenic behavior of murine spindle carcinoma cells. Possible involvement of plakoglobin.Semantic proximity Read ↗

Regulation of beta-catenin levels and localization by overexpression of plakoglobin and inhibition of the ubiquitin-proteasome system.Semantic proximity Read ↗

Plakoglobin induces desmosome formation and epidermoid phenotype in N-cadherin-expressing squamous carcinoma cells deficient in plakoglobin and E-cadherin.Semantic proximity Read ↗

Plakoglobin Regulates the Expression of the Anti-apoptotic Protein BCL-2Semantic proximity Read ↗

A Role for Endoglin as a Suppressor of Malignancy during Mouse Skin CarcinogenesisSemantic proximity Read ↗

Cell adhesion and tumor progression in mouse skin carcinogenesis: increased synthesis and organization of fibronectin is associated with the undifferentiated spindle phenotype.Semantic proximity Read ↗

Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription.Semantic proximity Read ↗

Plakoglobin restores tumor suppressor activity of p53R175H mutant by sequestering the oncogenic potential of β-catenin.Semantic proximity Read ↗

Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin.Semantic proximity Read ↗

Epidermal growth factor receptor inhibition promotes desmosome assembly and strengthens intercellular adhesion in squamous cell carcinoma cells.Semantic proximity Read ↗

Interaction of plakophilins with desmoplakin and intermediate filament proteins: an in vitro analysisSemantic proximity Read ↗

Defining the roles of beta-catenin and plakoglobin in LEF/T-cell factor-dependent transcription using beta-catenin/plakoglobin-null F9 cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.