Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A 700-kb physical map of a region of 16q23.2 homozygously deleted in multiple cancers and spanning the common fragile site FRA16D.

Cancer research - 15 Mar 2000

Paige A J, Taylor K J, Stewart A, Sgouros J G, Gabra H, Sellar G C, Smyth J F, Porteous D J, Watson J E

Abstract excerpt

We have identified a >600-kb region at 16q23.2 that is homozygously deleted from malignant ovarian ascites using representational difference analysis. Overlapping homozygous deletions were also observed in the colon carcinoma cell line HCT116 and a xenograft established from the small cell lung cancer cell line WX330. This region coincides with that described previously by others as showing loss of heterozygosity...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Banding
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Fragile Sites

Share to Chromosome Fragility

Share to Chromosomes, Artificial, Yeast

Share to Chromosomes, Human, Pair 16

Share to Contig Mapping

Share to Physical Chromosome Mapping

Source

Identifiers

PMID: 10749141

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A 700-kb physical map of a region of 16q23.2 homozygously deleted in multiple cancers and spanning the common fragile site FRA16D.PMID 10749141Read ↗

Identification and characterization of a 500-kb homozygously deleted region at 1p36.2-p36.3 in a neuroblastoma cell line.Semantic proximity Read ↗

Frequent genomic loss at chr16p13.2 is associated with poor prognosis in colorectal cancer.Semantic proximity Read ↗

Fine deletional mapping of chromosome 4q22-35 region in oral cancer.Semantic proximity Read ↗

Molecular basis for expression of common and rare fragile sites.Semantic proximity Read ↗

Molecular Biology of the WWOX Gene That Spans Chromosomal Fragile Site FRA16D.Semantic proximity Read ↗

Deletion at fragile sites is a common and early event in Barrett's esophagus.Semantic proximity Read ↗

FRA1E common fragile site breaks map within a 370kilobase pair region and disrupt the dihydropyrimidine dehydrogenase gene (DPYD).Semantic proximity Read ↗

Allelic imbalance mapping of chromosome 16 shows two regions of common deletion in prostate adenocarcinoma.Semantic proximity Read ↗

Characterization and screening for mutations of the growth arrest-specific 11 (GAS11) and C16orf3 genes at 16q24.3 in breast cancer.Semantic proximity Read ↗

Homozygous deletion map at 18q21.1 in pancreatic cancer.Semantic proximity Read ↗

DNA Instability at Chromosomal Fragile Sites in CancerSemantic proximity Read ↗

Smallest region of overlapping deletion in 1p36 in human neuroblastoma: A 1 Mbp cosmid and PAC contigSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.