Article
Characterization and screening for mutations of the growth arrest-specific 11 (GAS11) and C16orf3 genes at 16q24.3 in breast cancer.
Genomics - 15 Sept 1998
Whitmore S A, Settasatian C, Crawford J, Lower K M, McCallum B, Seshadri R, Cornelisse C J, Moerland E W, Cleton-Jansen A M, Tipping A J, Mathew C G, Savnio M, Savoia A, Verlander P, Auerbach A D, Van Berkel C, Pronk J C, Doggett N A, Callen D F
Abstract excerpt
Loss of heterozygosity involving the long arm of chromosome 16 is a frequent event seen in a number of human carcinomas, including breast, prostate, hepatocellular, and ovarian cancers. A region found to be commonly deleted in breast and prostate carcinomas is located at 16q24.3, which suggests t...
Topics
- Alleles
- Base Sequence
- Breast Neoplasms
- Chromosomes, Human, Pair 16
- Cloning, Molecular
- Cytoskeletal Proteins
- DNA Primers
- Female
- Gene Expression Regulation, Neoplastic
- Genes, Tumor Suppressor