Article
Molecular Biology of the WWOX Gene That Spans Chromosomal Fragile Site FRA16D.
Cells - 29 Jun 2021
Lee Cheng Shoou, Choo Amanda, Dayan Sonia, Richards Robert I, O'Keefe Louise V
Abstract excerpt
It is now more than 20 years since the FRA16D common chromosomal fragile site was characterised and the WWOX gene spanning this site was identified. In this time, much information has been discovered about its contribution to disease; however, the normal biological role of WWOX is not yet clear. Experiments leading to the identification of the WWOX gene are recounted, revealing enigmatic relationships between the...
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