Article
EGF signaling and ommatidial rotation in the Drosophila eye.
Current biology : CB - 19 Aug 2003
Strutt Helen, Strutt David
Abstract excerpt
The ommatidia of the Drosophila eye initiate development by stepwise recruitment of photoreceptors into symmetric ommatidial clusters. As they mature, the clusters become asymmetric, adopting opposite chirality on either side of the dorsoventral midline and rotating exactly 90 degrees (Figures 1A and 1B, ). The choice of chirality is governed by higher activity of the frizzled (fz) gene in one cell of the R3/R4...
Topics
- Animals
- Body Patterning
- Drosophila
- Drosophila Proteins
- Epidermal Growth Factor
- Eye
- Eye Proteins
- Frizzled Receptors
- Genes, Insect
- Green Fluorescent Proteins
- Luminescent Proteins
- Membrane Proteins
- Mutation
- Nerve Tissue Proteins
- Phenotype
- Photoreceptor Cells, Invertebrate
- Receptors, G-Protein-Coupled
- Recombinant Fusion Proteins