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Article

Molecular analysis of Drosophila eyes absent mutants reveals features of the conserved Eya domain.

Genetics - 1 Jun 2000

Bui Q T, Zimmerman J E, Liu H, Bonini N M

Abstract excerpt

The eyes absent (eya) gene is critical to eye formation in Drosophila; upon loss of eya function, eye progenitor cells die by programmed cell death. Moreover, ectopic eya expression directs eye formation, and eya functionally synergizes in vivo and physically interacts in vitro with two other genes of eye development, sine oculis and dachshund. The Eya protein sequence, while highly conserved to vertebrates, is...

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Identifiers

PMID: 10835393
DOI: 10.1093/genetics/155.2.709
PMCID: PMC1461105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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