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Article

A screen for genes that influence fibroblast growth factor signal transduction in Drosophila.

Genetics - 1 Jun 2005

Zhu Min Yan, Wilson Robert, Leptin Maria

Abstract excerpt

The misexpression of an activated form of the FGF receptor (FGFR) Breathless in conjunction with downstream-of-FGF-receptor (Dof), an essential signaling molecule of the FGF pathway, in the Drosophila eye imaginal discs impairs eye development and results in a rough eye phenotype. We used this phenotype in a gain-of-function screen to search for modifiers of FGF signaling. We identified 50 EP stocks with...

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Identifiers

PMID: 15834142
DOI: 10.1534/genetics.104.039750
PMCID: PMC1450423

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