Article
Genome-wide genetic screen identified the link between dG9a and epidermal growth factor receptor signaling pathway in vivo.
Experimental cell research - 1 Aug 2016
Shimaji Kouhei, Konishi Takahiro, Yoshida Hideki, Kimura Hiroshi, Yamaguchi Masamitsu
Abstract excerpt
G9a is one of the histone H3 Lys 9 (H3K9) specific methyltransferases first identified in mammals. Drosophila G9a (dG9a) has been reported to induce H3K9 dimethylation in vivo, and the target genes of dG9a were identified during embryonic and larval stages. Although dG9a is important for a variety of developmental processes, the link between dG9a and signaling pathways are not addressed yet. Here, by genome-wide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
