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Article

A screen for dominant mutations applied to components in the Drosophila EGF-R pathway.

Proceedings of the National Academy of Sciences of the United States of America - 19 Mar 2002

Guichard Annabel, Srinivasan Shaila, Zimm Georgianna, Bier Ethan

Abstract excerpt

The Drosophila epidermal growth factor receptor (EGF-R) controls many critical cell fate choices throughout development. Several proteins collaborate to promote localized EGF-R activation, such as Star and Rhomboid (Rho), which act sequentially to ensure the maturation and processing of inactive membrane-bound EGF ligands. To gain insights into the mechanisms underlying Rho and Star function, we developed a...

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Identifiers

PMID: 11904431
DOI: 10.1073/pnas.052028699
PMCID: PMC122596

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A screen for dominant mutations applied to components in the Drosophila EGF-R pathway.PMID 11904431Read ↗

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