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Article

Subunit composition and novel localization of K+ channels in spinal cord

1 Jan 2000

Abstract excerpt

Axonal K+ channels involved in normal spinal cord function are candidate targets for therapeutics, which improve sensorimotor function in spinal cord injury. To this end, we have investigated the expression, localization, and coassociation of Kv1 alpha and beta subunits in human, rat, and bovine spinal cord. We find that Kv1.1, Kv1.2, and Kvbeta2 form heteromultimeric complexes at juxtaparanodal zones in...

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PMID: 11086297
DOI: 10.1002/1096-9861(20000101)429:1<166::aid-cne13>3.0.co;2-y

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