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Article

Ancestral bias in the Hras1 gene and distal Chromosome 7 among inbred mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2007

Drew Jennifer C, Kastenmeier Andrew S, Drinkwater Norman R

Abstract excerpt

Inbred strains of mice vary in their frequency of liver tumors initiated by a mutation in the Hras1 (H-ras) proto-oncogene. We sequenced 4.5 kb of the Hras1 gene on distal Chr 7 in a diverse set of 12 commonly used laboratory inbred strains of mice and detected no sequence variation to account for strain-specific differences in Hras1 mutation prevalence. Furthermore, the Hras1 sequence is essentially monoallelic...

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Source

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Identifiers

PMID: 17906893
DOI: 10.1007/s00335-007-9061-1
PMCID: PMC2042029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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