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Article

A condition for successful escape of a mutant after primary HIV infection.

Journal of theoretical biology - 21 Apr 2000

Monteiro L H, Gonçalves C H, Piqueira J R

Abstract excerpt

Cytotoxic T lymphocytes (CTLs) vigorously restrict primary human immunodeficiency virus (HIV) infection. However, the frequently erroneous process of viral replication favors the creation of mutants not recognizable by primary CTLs. Variants that tolerate the mutations may have selective advantage and may increase in abundance, until the immune system reacts against them. Therefore, such variants represent a way...

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Source

Identifiers

PMID: 10736216
DOI: 10.1006/jtbi.2000.1092

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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