Article
Human natural killer T cells acquire a memory-activated phenotype before birth.
Blood - 1 Apr 2000
van Der Vliet H J, Nishi N, de Gruijl T D, von Blomberg B M, van den Eertwegh A J, Pinedo H M, Giaccone G, Scheper R J
Abstract excerpt
Natural killer T (NKT) cells have recently been shown to play an important role in the rejection of malignant tumors and in the regulation of autoimmune diseases. Potent antitumor effects of the marine sponge-derived NKT cell ligand KRN7000 were observed in mice. Therefore, the elucidation of the natural ligand of NKT cells, which is currently still unknown, might have important clinical consequences for the...
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