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Article

Human NK cell education by inhibitory receptors for MHC class I.

Immunity - 1 Aug 2006

Anfossi Nicolas, André Pascale, Guia Sophie, Falk Christine S, Roetynck Sophie, Stewart C Andrew, Breso Violette, Frassati Coralie, Reviron Denis, Middleton Derek, Romagné François, Ugolini Sophie, Vivier Eric

Abstract excerpt

Natural killer (NK) cells recognize the absence of self MHC class I as a way to discriminate normal cells from cells in distress. In humans, this "missing self" recognition is ensured by inhibitory receptors such as KIR, which dampen NK cell activation upon interaction with their MHC class I ligands. We show here that NK cells lacking inhibitory KIR for self MHC class I molecules are present in human peripheral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16901727
DOI: 10.1016/j.immuni.2006.06.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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