Article
Human NK cells display major phenotypic and functional changes over the life span.
Aging cell - 1 Aug 2010
Le Garff-Tavernier Magali, Béziat Vivien, Decocq Julie, Siguret Virginie, Gandjbakhch Frédérique, Pautas Eric, Debré Patrice, Merle-Beral Hélène, Vieillard Vincent
Abstract excerpt
Aging is generally associated with an increased predisposition to infectious diseases and cancers, related in part to the development of immune senescence, a process that affects all cell compartments of the immune system. Although many studies have investigated the effects of age on natural killer (NK) cells, their conclusions remain controversial because the diverse health status of study subjects resulted in...
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