Article
Frequent expression of the natural killer cell receptor KLRG1 in human cord blood T cells: correlation with replicative history.
European journal of immunology - 1 Oct 2004
Marcolino Isabel, Przybylski Grzegorz K, Koschella Marie, Schmidt Christian A, Voehringer David, Schlesier Michael, Pircher Hanspeter
Abstract excerpt
The killer cell lectin-like receptor G1 (KLRG1) belongs to the family of inhibitory C-type lectins that are encoded in the NK gene complex. Similar to other inhibitory NK cell receptors, KLRG1 expression in adult peripheral blood lymphocytes is restricted to NK cells and to antigen-experienced T cells. Umbilical cord blood T cells are thought to represent an homogenous pool of naive T cells. Surprisingly, we...
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