Evidence for eomesodermin‐expressing innate‐like CD8⁺ KIR/NKG2A⁺ T cells in human adults and cord blood samples

Abstract excerpt

Polyclonal CD8(+) T cells, with a marked innate/memory phenotype, high eomesodermin (Eomes) expression, and the capacity to generate IFN-γ rapidly without prior exposure to antigen, have been described in mice. However, even though a pool of human CD8(+) T cells expressing killer Ig-like receptors (KIRs) was recently documented, the existence of a human equivalent of murine innate/memory CD8(+) T cells remains to...

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