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Article

Human congenital infection with Trypanosoma cruzi induces phenotypic and functional modifications of cord blood NK cells.

Pediatric research - 1 Jul 2006

Hermann Emmanuel, Alonso-Vega Cristina, Berthe Aurelie, Truyens Carine, Flores Amilcar, Cordova Marisol, Moretta Lorenzo, Torrico Faustino, Braud Veronique, Carlier Yves

Abstract excerpt

We studied the phenotype and activity of cord blood natural killer (NK) cells in newborns congenitally infected with Trypanosoma cruzi. We found that the proportion of CD56(bright) NK cells was significantly decreased in cord blood from these newborns, suggesting they may have been recruited to secondary lymphoid organs. The remaining CD56(bright) NK cells exhibited a defective ability in the production of...

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PMID: 16690951
DOI: 10.1203/01.pdr.0000220335.05588.ea

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Source receipt: pubmed, retrieved 7 Sept 2026.

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