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Limited correlation between human thymus and blood NKT cell content revealed by an ontogeny study of paired tissue samples

7 Apr 2005

Abstract excerpt

NKT cells are a CD1d-restricted T cell subset with strong immunoregulatory properties. Human NKT deficiencies are associated with autoimmune diseases such as type 1 diabetes and several types of cancer, yet there is little understanding of how the human NKT cell pool develops or is maintained. In this study, we present the first detailed analysis of human NKT cells from donor-matched postnatal thymus and blood...

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PMID: 15816002
DOI: 10.1002/eji.200425958

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