Article

Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR <sup>+</sup> NKG2A <sup>-</sup> NK cells

2020-01-27

Abstract excerpt

Despite their identification several years ago, molecular identity and developmental relation between human ILC1 and NK cells, comprising group 1 ILCs, is still elusive. To unravel their connection, thorough transcriptional, epigenetic, and functional characterization was performed from umbilical cord blood (CB). Unexpectedly, ILC1-like cells lacked Tbet expression and failed to produce IFNg. Moreover, in contrast...

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Literature Corpus work: 23613f21-bd8f-532d-9c4b-5e9fed188421
DOI: 10.1101/2020.01.24.918318

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