Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells

13 Jul 2020

Abstract excerpt

Despite their identification several years ago, molecular identity and developmental relation between human ILC1 and NK cells, comprising group 1 ILCs, is still elusive. To unravel their connection, thorough transcriptional, epigenetic, and functional characterization was performed from umbilical cord blood (CB). Unexpectedly, ILC1-like cells lacked Tbet expression and failed to produce IFNγ. Moreover, in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Eosinophilic Esophagitis
Share to IL-33, ST2, and ILC Pathways
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32657756
DOI: 10.7554/elife.55232

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cellsPMID 32657756Read ↗

Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR <sup>+</sup> NKG2A <sup>-</sup> NK cellsSemantic proximity Read ↗

Embryonic and neonatal waves generate distinct populations of hepatic ILC1sSemantic proximity Read ↗

Single-cell RNA sequencing identifies a population of human liver-type ILC1sSemantic proximity Read ↗

Diversity of human NK cell developmental pathways defined by single-cell analyses.Semantic proximity Read ↗

Distinct tissue-dependent composition and gene expression of human fetal innate lymphoid cellsSemantic proximity Read ↗

Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood.Semantic proximity Read ↗

Multifaceted characterization of the biological and transcriptomic signatures of natural killer cells derived from cord blood and placental bloodSemantic proximity Read ↗

Umbilical Cord Blood and iPSC-Derived Natural Killer Cells Demonstrate Key Differences in Cytotoxic Activity and KIR Profiles.Semantic proximity Read ↗

Human Natural Killer T Cells Are Heterogeneous in Their Capacity to Reprogram Their Effector FunctionsSemantic proximity Read ↗

Frequent expression of the natural killer cell receptor KLRG1 in human cord blood T cells: correlation with replicative history.Semantic proximity Read ↗

Development of Human ILCs and Impact of Unconventional Cytotoxic Subsets in the Pathophysiology of Inflammatory Diseases and CancerSemantic proximity Read ↗

Phenotypic and functional heterogeneity of human NK cells developing after umbilical cord blood transplantation: a role for human cytomegalovirus?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.